A Robust Protocol for Differentiation and Expansion of hPSC-derived NK Cells
Jiaqi Sun, Huisheng Liu, Hui Sun, Yanzhuo Ye, Shasha Huang, Shahang Luo, Qianqian Liu
DOI: 10.52601/bpr.2026.260027
Abstract PDF
In vitro maturation of affinity of CD antibodies by CHO cell display
Qian Yao, Zhishang Hu, Yang Cao, Junying Jia, Ruiqi Luo, Xin Zhang, Shu Meng, Haiying Hang, Yun Zhao, Yanshu Zhang
DOI: 10.52601/bpr.2026.260036
Abstract PDF
Targeting the GDF15-GFRAL Pathway in NSCLC Cachexia: From Stress Responses to Targeted Therapies
Puneeth Iyengar, Xiaotong Zhu, Natalie Lopez, Jinhai Yu, Naureen Wajahat, Tong Guo, Rodney E. Infante, Andrey Popugailo, Arun Gupta
DOI: 10.52601/bpr.2026.260030
Abstract PDF
CRISPR-Cas9-mediated genome editing in Caenorhabditis elegans using in-house purified Cas9 protein and sgRNAs
Gang Wan, Haiqian Ma
DOI: 10.52601/bpr.2026.260029
Abstract PDF
Neuronal Traction Force: From Growth Cone Motility to Neuronal Development, Migration, and Regeneration
Yuan Feng, Lefan Lv, Qian Suo, Shengyuan Ma, Guang-Zhong Yang, Assaf Zemel, Huijing Jin, Linyong Zhu, Peiyan Duan
DOI: 10.52601/bpr.2026.260028
Abstract PDF
Unraveling Dynamic Molecular Networks through the Evolution of Proximity Labeling Technologies
Weihong Fu, Wenxiu Ning, Lin Xie, Lijuan Gao, Hua Li
DOI: 10.52601/bpr.2026.260014
Abstract PDF
A protocol for fast observation and study of the nuclear surface ultrastructure in adherent cultured somatic cells
Chuanmao Zhang, Gan Zhao, He Ren, Guangwei Xin, Xiangyang Wang
DOI: 10.52601/bpr.2026.260008
Abstract PDF
mRNA Degradation Pathways in E. coli
Yizina Yilihamujiang, Jingge Wang, Ang Gao
DOI: 10.52601/bpr.2026.260015
Abstract PDF
Mechanistic Insights into Cryo-cooling Induced Conformational Biases in Protein Crystal and Solution Environments
Yi Xue, Jiahui Sun
DOI: 10.52601/bpr.2026.260007
Abstract PDF
When Water Matters: NMR of Molecular Structure and Dynamics under Native Hydration
Kai Xue, Yulun Chen, Choon-Peng Chng, Changjin Huang, Yiting Pang
DOI: 10.52601/bpr.2026.260005
Abstract PDF
Deep Learning from CT Scans Assists Diagnosis of Papillary Renal Cell Carcinoma Subtypes
Hongqian Guo, Kuangyu Shi, Yansheng Kan, Yu Zhao
DOI: 10.52601/bpr.2025.250040
Abstract PDF
Articles in press have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
Innovation in SPR-based molecular fishing: development and applications of an indigenous Chinese platform
Qing Chang, Jun Lan, Weihua Wang, Yukai Ma, Biao Wang, Mengyun Shi, Zi Yang, Wendan Chu, Bin Zhou, Wenqi Li
DOI: 10.52601/bpr.2026.260002
Abstract FullText HTML PDF
Using stable isotope and click-chemistry probes to study fatty acid flux in cancer cells
Rifah Rownak Tanshee, Mingjun Tan, Qin Li, Shengyu Yang, Yunzhan Li
DOI: 10.52601/bpr.2026.260018
Abstract FullText HTML PDF
Quantitative full-length transcriptome analysis by nanopore sequencing with error-aware UMI mapping
Qingwen Li, Guangtao Song, Jizhong Lou, Dongxu Li, Chen Sun, Yihua Huang
DOI: 10.52601/bpr.2026.260010
Abstract FullText HTML PDF
Minor apolipoproteins contribute to the pleiotropic effects of high-density lipoprotein
Makoto Kurano, Shengyi Liu, Kazuhisa Tsukamoto, Yutaka Yatomi, Teruhiko Yoshida
DOI: 10.52601/bpr.2026.260001
Abstract FullText HTML PDF
Hexameric assembly of the orai1 channel determined using targeted cryo-electron tomography in situ
Xiaolan Xu, Yanhong Xue, Xiaojun Xu, Tongxin Niu, Jun Guo, Liqing Liu
DOI: 10.52601/bpr.2026.250055
Abstract FullText HTML PDF
Lipid droplets and viruses: a dynamic battlefield of cellular resources
Zifang Zheng, Xue Ling, Jie Wu, Shuqi Xiao, Shuang Qiao, Shuangquan Zhang
DOI: 10.52601/bpr.2026.250053
Abstract FullText HTML PDF
The current status of medicine development for precision therapy and diagnosis targeting KRASG12C
Gui-Long Tian, Fan Wang, Chengyu Zhang
DOI: 10.52601/bpr.2026.250060
Abstract FullText HTML PDF
Screening for putative essential genes in Brucella abortus strains A19 and S2308 using transposon mutagenesis
Jian Xu, Yuefeng Chu, Weidong Bu, Liyuan Liu, Siwei Guo, Fangfang Guo, Dianyu Li, Xiaxia Liu
DOI: 10.52601/bpr.2025.250050
Abstract FullText HTML PDF
Design optimization and characterization of a dual-reporter Nipah virus pseudovirus
Yingjie Sun, Yang Qu, Xusheng Qiu, Ying Liao, Ruixin Kuang, Lei Tan, Chan Ding, Ruijuan Xu, Cuiping Song, Yufei Tian
DOI: 10.52601/bpr.2025.250063
Abstract FullText HTML PDF
Mechanistic insights into viral−host interactions during transcription
Zirui Li, Guoliang Zhu, Zehong Huang, Tingyu Peng, Zixiang Zhu
DOI: 10.52601/bpr.2026.250066
Abstract FullText HTML PDF
Mechanism of irreversible conformational locking in the SARS-CoV-2 spike protein induced by transient molecular binding
Zijian Liu, Xiang Fan, Mengke Jia, Hongqi Ai, Chuanbo Wang, Yüning Guan
DOI: 10.52601/bpr.2025.250051
Abstract FullText HTML PDF
Structure-based prediction reveals FAM105A as an African swine fever virus I215L interactor
Shilei Zhang, Fayu Yang, Danyang Zhang, Xing Chen, Yuxi Yang
DOI: 10.52601/bpr.2025.250057
Abstract FullText HTML PDF
Potential therapeutic effect of stem cells on sensorineural hearing loss
Xiong Chen, Zilin Huang, Keshu Liu
DOI: 10.52601/bpr.2025.240017
Abstract FullText HTML PDF
Chemical dissection of sterol and bile acid signaling via clickable photoaffinity probes
Xiaoming Chen, Miaomiao Xu, Xinglin Yang, Jian Ma
DOI: 10.52601/bpr.2025.250029
Abstract FullText HTML PDF
Methods and advances in RNA segment-selective labelling
Zixuan Hu, Xianyang Fang, Shiping Yang
DOI: 10.52601/bpr.2025.250037
Abstract FullText HTML PDF
Research progress of phage anti-CRISPR proteins
Mengwen Zhao, Ang Gao, Yalan Zhu
DOI: 10.52601/bpr.2025.250025
Abstract FullText HTML PDF
A protocol for detection of mitochondrial protein malonylation and succinylation
Hao Hu, Xiaoqing Cao, Jifeng Wang, Taotao Wei, Juncheng Zhao, Sunyuntao Xu, Min Xiao, Xiaoxia Pei
DOI: 10.52601/bpr.2025.250047
Abstract FullText HTML PDF
Allosteric regulation of C-reactive protein
Zhenyu Yao, Margaret E. Olson, Marc Potempa, Lawrence A. Potempa, Jianmin Lv, Ibraheem M. Rajab
DOI: 10.52601/bpr.2025.250041
Abstract FullText HTML PDF
Strategies and mechanisms of radiosensitization in cancer therapy
Fan Wang, Gaoyuan Xie, Xiaotu Ma
DOI: 10.52601/bpr.2025.250056
Abstract FullText HTML PDF
Neutrophils extracellular traps-related lncRNAs as potential biomarkers in lung adenocarcinoma
Yingli Chen, Yuanyuan Zhao, Qianzhong Li
DOI: 10.52601/bpr.2025.250058
Abstract FullText HTML PDF
Nanobody PET tracer enables GPA33 expression profiling for precision diagnosis of colorectal cancer
Sixuan Cheng, Hao Yang, Weibo Cai, Dawei Jiang, Shaowen Yang, Weijun Wei, Chengwen Zheng, Wenbo Li, Zhidie Huang
DOI: 10.52601/bpr.2025.250034
Abstract FullText HTML PDF
A computational-experimental strategy identifies K-7174 against African swine fever
Haixue Zheng, Guoliang Zhu, Fei Xi, Yifei Zhao, Zixiang Zhu, Huanan Liu, Bozhang Sun, Zhirui Liu, Haiyang Song
DOI: 10.52601/bpr.2025.250054
Abstract FullText HTML PDF
Step-by-step procedure for an optimized serial lift-out cryo-focused ion beam milling technique in tissue analysis
Jiaming Liu, Jingtao Zheng, Xiaoyu Tang, Huanhuan Huang, Meijing Li, Peng Wang, Ying Liu, Zihang Yu
DOI: 10.52601/bpr.2025.250039
Abstract FullText HTML PDF
Targeting coronaviral nsp14: a bifunctional enzyme for RNA capping and proofreading
Zhiyong Lou, Yixiao Liu, Junbo Wang
DOI: 10.52601/bpr.2025.250036
Abstract FullText HTML PDF
[64Cu]Cu-NOTA-Ivonescimab: a novel PET tracer for imaging VEGF expression in colorectal carcinoma
Jonathan W. Engle, Wenpeng Huang, Ruobing Li, Yihan Yang, Weibo Cai, Lei Kang, Molly C. DeLuca, Jessica C. Hsu, Yuchun Wei, Liming Li, Yongshun Liu
DOI: 10.52601/bpr.2025.250031
Abstract FullText HTML PDF
Molecular mechanisms of CBASS-mediated bacteriophage defense
Yao Ge, Ang Gao, Yalan Zhu
DOI: 10.52601/bpr.2025.250028
Abstract FullText HTML PDF
Cyclic stretch and oxidative stress induced miRNAs in vascular remodeling
Ziqi Shang, Kai Huang
DOI: 10.52601/bpr.2025.250033
Abstract FullText HTML PDF
Interactions between membrane proteins and lipid membrane revealed by cryoEM
Yusong R. Guo, Xinying Liu, Sixian He, Yun Han
DOI: 10.52601/bpr.2025.240073
Abstract FullText HTML PDF
Articles in press have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
A Robust Protocol for Differentiation and Expansion of hPSC-derived NK Cells
Jiaqi Sun, Huisheng Liu, Hui Sun, Yanzhuo Ye, Shasha Huang, Shahang Luo, Qianqian Liu
DOI: 10.52601/bpr.2026.260027
Abstract PDF
In vitro maturation of affinity of CD antibodies by CHO cell display
Qian Yao, Zhishang Hu, Yang Cao, Junying Jia, Ruiqi Luo, Xin Zhang, Shu Meng, Haiying Hang, Yun Zhao, Yanshu Zhang
DOI: 10.52601/bpr.2026.260036
Abstract PDF
Targeting the GDF15-GFRAL Pathway in NSCLC Cachexia: From Stress Responses to Targeted Therapies
Puneeth Iyengar, Xiaotong Zhu, Natalie Lopez, Jinhai Yu, Naureen Wajahat, Tong Guo, Rodney E. Infante, Andrey Popugailo, Arun Gupta
DOI: 10.52601/bpr.2026.260030
Abstract PDF
Innovation in SPR-based molecular fishing: development and applications of an indigenous Chinese platform
Qing Chang, Jun Lan, Weihua Wang, Yukai Ma, Biao Wang, Mengyun Shi, Zi Yang, Wendan Chu, Bin Zhou, Wenqi Li
DOI: 10.52601/bpr.2026.260002
Abstract FullText HTML PDF
Using stable isotope and click-chemistry probes to study fatty acid flux in cancer cells
Rifah Rownak Tanshee, Mingjun Tan, Qin Li, Shengyu Yang, Yunzhan Li
DOI: 10.52601/bpr.2026.260018
Abstract FullText HTML PDF
Quantitative full-length transcriptome analysis by nanopore sequencing with error-aware UMI mapping
Qingwen Li, Guangtao Song, Jizhong Lou, Dongxu Li, Chen Sun, Yihua Huang
DOI: 10.52601/bpr.2026.260010
Abstract FullText HTML PDF
Minor apolipoproteins contribute to the pleiotropic effects of high-density lipoprotein
Makoto Kurano, Shengyi Liu, Kazuhisa Tsukamoto, Yutaka Yatomi, Teruhiko Yoshida
DOI: 10.52601/bpr.2026.260001
Abstract FullText HTML PDF
CRISPR-Cas9-mediated genome editing in Caenorhabditis elegans using in-house purified Cas9 protein and sgRNAs
Gang Wan, Haiqian Ma
DOI: 10.52601/bpr.2026.260029
Abstract PDF
Neuronal Traction Force: From Growth Cone Motility to Neuronal Development, Migration, and Regeneration
Yuan Feng, Lefan Lv, Qian Suo, Shengyuan Ma, Guang-Zhong Yang, Assaf Zemel, Huijing Jin, Linyong Zhu, Peiyan Duan
DOI: 10.52601/bpr.2026.260028
Abstract PDF
Unraveling Dynamic Molecular Networks through the Evolution of Proximity Labeling Technologies
Weihong Fu, Wenxiu Ning, Lin Xie, Lijuan Gao, Hua Li
DOI: 10.52601/bpr.2026.260014
Abstract PDF
Hexameric assembly of the orai1 channel determined using targeted cryo-electron tomography in situ
Xiaolan Xu, Yanhong Xue, Xiaojun Xu, Tongxin Niu, Jun Guo, Liqing Liu
DOI: 10.52601/bpr.2026.250055
Abstract FullText HTML PDF
A protocol for fast observation and study of the nuclear surface ultrastructure in adherent cultured somatic cells
Chuanmao Zhang, Gan Zhao, He Ren, Guangwei Xin, Xiangyang Wang
DOI: 10.52601/bpr.2026.260008
Abstract PDF
mRNA Degradation Pathways in E. coli
Yizina Yilihamujiang, Jingge Wang, Ang Gao
DOI: 10.52601/bpr.2026.260015
Abstract PDF
Lipid droplets and viruses: a dynamic battlefield of cellular resources
Zifang Zheng, Xue Ling, Jie Wu, Shuqi Xiao, Shuang Qiao, Shuangquan Zhang
DOI: 10.52601/bpr.2026.250053
Abstract FullText HTML PDF
The current status of medicine development for precision therapy and diagnosis targeting KRASG12C
Gui-Long Tian, Fan Wang, Chengyu Zhang
DOI: 10.52601/bpr.2026.250060
Abstract FullText HTML PDF
Screening for putative essential genes in Brucella abortus strains A19 and S2308 using transposon mutagenesis
Jian Xu, Yuefeng Chu, Weidong Bu, Liyuan Liu, Siwei Guo, Fangfang Guo, Dianyu Li, Xiaxia Liu
DOI: 10.52601/bpr.2025.250050
Abstract FullText HTML PDF
Design optimization and characterization of a dual-reporter Nipah virus pseudovirus
Yingjie Sun, Yang Qu, Xusheng Qiu, Ying Liao, Ruixin Kuang, Lei Tan, Chan Ding, Ruijuan Xu, Cuiping Song, Yufei Tian
DOI: 10.52601/bpr.2025.250063
Abstract FullText HTML PDF
Mechanistic insights into viral−host interactions during transcription
Zirui Li, Guoliang Zhu, Zehong Huang, Tingyu Peng, Zixiang Zhu
DOI: 10.52601/bpr.2026.250066
Abstract FullText HTML PDF
Mechanism of irreversible conformational locking in the SARS-CoV-2 spike protein induced by transient molecular binding
Zijian Liu, Xiang Fan, Mengke Jia, Hongqi Ai, Chuanbo Wang, Yüning Guan
DOI: 10.52601/bpr.2025.250051
Abstract FullText HTML PDF
Mechanistic Insights into Cryo-cooling Induced Conformational Biases in Protein Crystal and Solution Environments
Yi Xue, Jiahui Sun
DOI: 10.52601/bpr.2026.260007
Abstract PDF
When Water Matters: NMR of Molecular Structure and Dynamics under Native Hydration
Kai Xue, Yulun Chen, Choon-Peng Chng, Changjin Huang, Yiting Pang
DOI: 10.52601/bpr.2026.260005
Abstract PDF
Structure-based prediction reveals FAM105A as an African swine fever virus I215L interactor
Shilei Zhang, Fayu Yang, Danyang Zhang, Xing Chen, Yuxi Yang
DOI: 10.52601/bpr.2025.250057
Abstract FullText HTML PDF
Potential therapeutic effect of stem cells on sensorineural hearing loss
Xiong Chen, Zilin Huang, Keshu Liu
DOI: 10.52601/bpr.2025.240017
Abstract FullText HTML PDF
Chemical dissection of sterol and bile acid signaling via clickable photoaffinity probes
Xiaoming Chen, Miaomiao Xu, Xinglin Yang, Jian Ma
DOI: 10.52601/bpr.2025.250029
Abstract FullText HTML PDF
Methods and advances in RNA segment-selective labelling
Zixuan Hu, Xianyang Fang, Shiping Yang
DOI: 10.52601/bpr.2025.250037
Abstract FullText HTML PDF
Research progress of phage anti-CRISPR proteins
Mengwen Zhao, Ang Gao, Yalan Zhu
DOI: 10.52601/bpr.2025.250025
Abstract FullText HTML PDF
A protocol for detection of mitochondrial protein malonylation and succinylation
Hao Hu, Xiaoqing Cao, Jifeng Wang, Taotao Wei, Juncheng Zhao, Sunyuntao Xu, Min Xiao, Xiaoxia Pei
DOI: 10.52601/bpr.2025.250047
Abstract FullText HTML PDF
Allosteric regulation of C-reactive protein
Zhenyu Yao, Margaret E. Olson, Marc Potempa, Lawrence A. Potempa, Jianmin Lv, Ibraheem M. Rajab
DOI: 10.52601/bpr.2025.250041
Abstract FullText HTML PDF
Deep Learning from CT Scans Assists Diagnosis of Papillary Renal Cell Carcinoma Subtypes
Hongqian Guo, Kuangyu Shi, Yansheng Kan, Yu Zhao
DOI: 10.52601/bpr.2025.250040
Abstract PDF
Strategies and mechanisms of radiosensitization in cancer therapy
Fan Wang, Gaoyuan Xie, Xiaotu Ma
DOI: 10.52601/bpr.2025.250056
Abstract FullText HTML PDF
Neutrophils extracellular traps-related lncRNAs as potential biomarkers in lung adenocarcinoma
Yingli Chen, Yuanyuan Zhao, Qianzhong Li
DOI: 10.52601/bpr.2025.250058
Abstract FullText HTML PDF
Nanobody PET tracer enables GPA33 expression profiling for precision diagnosis of colorectal cancer
Sixuan Cheng, Hao Yang, Weibo Cai, Dawei Jiang, Shaowen Yang, Weijun Wei, Chengwen Zheng, Wenbo Li, Zhidie Huang
DOI: 10.52601/bpr.2025.250034
Abstract FullText HTML PDF
A computational-experimental strategy identifies K-7174 against African swine fever
Haixue Zheng, Guoliang Zhu, Fei Xi, Yifei Zhao, Zixiang Zhu, Huanan Liu, Bozhang Sun, Zhirui Liu, Haiyang Song
DOI: 10.52601/bpr.2025.250054
Abstract FullText HTML PDF
Step-by-step procedure for an optimized serial lift-out cryo-focused ion beam milling technique in tissue analysis
Jiaming Liu, Jingtao Zheng, Xiaoyu Tang, Huanhuan Huang, Meijing Li, Peng Wang, Ying Liu, Zihang Yu
DOI: 10.52601/bpr.2025.250039
Abstract FullText HTML PDF
Targeting coronaviral nsp14: a bifunctional enzyme for RNA capping and proofreading
Zhiyong Lou, Yixiao Liu, Junbo Wang
DOI: 10.52601/bpr.2025.250036
Abstract FullText HTML PDF
[64Cu]Cu-NOTA-Ivonescimab: a novel PET tracer for imaging VEGF expression in colorectal carcinoma
Jonathan W. Engle, Wenpeng Huang, Ruobing Li, Yihan Yang, Weibo Cai, Lei Kang, Molly C. DeLuca, Jessica C. Hsu, Yuchun Wei, Liming Li, Yongshun Liu
DOI: 10.52601/bpr.2025.250031
Abstract FullText HTML PDF
Molecular mechanisms of CBASS-mediated bacteriophage defense
Yao Ge, Ang Gao, Yalan Zhu
DOI: 10.52601/bpr.2025.250028
Abstract FullText HTML PDF
Cyclic stretch and oxidative stress induced miRNAs in vascular remodeling
Ziqi Shang, Kai Huang
DOI: 10.52601/bpr.2025.250033
Abstract FullText HTML PDF
Interactions between membrane proteins and lipid membrane revealed by cryoEM
Yusong R. Guo, Xinying Liu, Sixian He, Yun Han
DOI: 10.52601/bpr.2025.240073
Abstract FullText HTML PDF
column
Optimized workflow of site-specific cryo-lamella preparation for cryo-ET using integrated light and electron microscope
Jiali Xie, Wei Ji, Maoge Zhou, Weixing Li, Yuanyuan Li, Ke Xiao
2026, 12(4) DOI: 10.52601/bpr.2025.250016
Abstract FullText HTML PDF
Optimized tissue sample preparation for cryo-electron tomography using serial lift-out
Qiang Guo, Junhan Yang, Wenjing Du
2026, 12(4) DOI: 10.52601/bpr.2025.250035
Abstract FullText HTML PDF
Emerging trends of fluorescence lifetime imaging microscopy (FLIM): advances, challenges, and prospects
Meilin Li, Baoyi Wang, Xiaoshuai Huang, Bei Liu
2026, 12(4) DOI: 10.52601/bpr.2025.250024
Abstract FullText HTML PDF
Advances in label-free dynamic imaging of live cells using fourier ptychographic microscopy
Yong Liu, Hongda Wang, Houliang He, Yangang Pan, Lina Shao, Fei Sun, Dayu Li
2026, 12(4) DOI: 10.52601/bpr.2025.250017
Abstract FullText HTML PDF
Optical diffraction tomographic microscopy: a cutting-edge label-free three-dimensional bioimaging
Peng Gao, Baoli Yao, Yingjie Feng, Ruihua Liu, Yan Li, Junwei Min, Kai Wen, Siying Wang, Tengfei Wu, Liming Yang, Yuge Xue, Xun Yuan
2026, 12(4) DOI: 10.52601/bpr.2025.250026
Abstract FullText HTML PDF
Advances in scanning probe microscopy for biological systems
Songping He, Weixing Li, Qing Huan, Xiaodong Yu, Wei Ji
2026, 12(4) DOI: 10.52601/bpr.2025.250023
Abstract FullText HTML PDF
Structural plasticity of mouse intestinal microvilli revealed by tissue-level cryo-ET
Ying Liu, Zihang Yu, Jingtao Zheng, Meijing Li, Huanhuan Huang, Xiaoyu Tang, Jiaming Liu, Peng Wang
2026, 12(4) DOI: 10.52601/bpr.2025.250038
Abstract FullText HTML PDF
Stem cell-derived exosomes preserve diabetic islet function: a systematic review and meta-analysis of preclinical studies
Lizhe Cai, Yingling Jiang, Zhihua Dou, Tongran Zhang, Yan Hu, Xu Wei, Haopeng Lin, Yanying Guo, Huisheng Liu, Xin Liu, Lihua Chen
2026, 12(4) DOI: 10.52601/bpr.2026.250071
Abstract FullText HTML PDF