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An Gong, Mingwei Min. Measuring the size and growth of single cells[J]. Biophysics Reports, 2022, 8(3): 150-157. doi: 10.52601/bpr.2022.210036
Citation: An Gong, Mingwei Min. Measuring the size and growth of single cells[J]. Biophysics Reports, 2022, 8(3): 150-157. doi: 10.52601/bpr.2022.210036

Measuring the size and growth of single cells

doi: 10.52601/bpr.2022.210036
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  • Corresponding author: min_mingwei@grmh-gdl.cn
  • Received Date: 13 July 2021
  • Accepted Date: 28 December 2021
  • Available Online: 24 February 2022
  • Publish Date: 22 June 2022
  • The size and growth of a cell can be described by three related physical parameters: volume, density and mass. All the three are coupled to numerous biochemical reactions and biophysical properties of a cell. It is therefore not surprising that cell size and growth pattern are tightly regulated across all kingdoms of life. Indeed, deregulation of cell size and growth has been found to be associated with diseases. Yet, how cells regulate their size and how cell size connects to cell function remain poorly understood, partly due to the difficulties to precisely measure the size and growth of single cells. In this review, we summarize methods of measuring cell volume, density, and mass, and discuss how the new technologies may advance our understanding of cell size control.

  • An Gong and Mingwei Min declare that they have no conflict of interest.
    This article does not contain any studies with human or animal subjects performed by any of the authors.

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