Volume 10 Issue 2
Apr.  2024
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Qiuyuan Yin, Chonglin Yang. Exploring lysosomal biology: current approaches and methods. Biophysics Reports, 2024, 10(2): 111-120. doi: 10.52601/bpr.2023.230028
Citation: Qiuyuan Yin, Chonglin Yang. Exploring lysosomal biology: current approaches and methods. Biophysics Reports, 2024, 10(2): 111-120. doi: 10.52601/bpr.2023.230028

Exploring lysosomal biology: current approaches and methods

doi: 10.52601/bpr.2023.230028
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  • Corresponding author: qiuyuan_yin@ynu.edu.cn (Q. Yin); clyang@ynu.edu.cn (C. Yang)
  • Received Date: 28 October 2023
  • Accepted Date: 04 January 2024
  • Available Online: 26 February 2024
  • Publish Date: 30 April 2024
  • Lysosomes are the degradation centers and signaling hubs in the cell. Lysosomes undergo adaptation to maintain cell homeostasis in response to a wide variety of cues. Dysfunction of lysosomes leads to aging and severe diseases including lysosomal storage diseases (LSDs), neurodegenerative disorders, and cancer. To understand the complexity of lysosome biology, many research approaches and tools have been developed to investigate lysosomal functions and regulatory mechanisms in diverse experimental systems. This review summarizes the current approaches and tools adopted for studying lysosomes, and aims to provide a methodological overview of lysosomal research and related fields.

  • Qiuyuan Yin and Chonglin Yang declare that they have no conflict of interest.
    This article does not contain any studies with human or animal subjects performed by any of the authors.

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