Volume 10 Issue 2
Apr.  2024
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Yuwei Huang, Li Yu. Seeing is believing: observation of migrasomes. Biophysics Reports, 2024, 10(2): 67-81. doi: 10.52601/bpr.2023.230024
Citation: Yuwei Huang, Li Yu. Seeing is believing: observation of migrasomes. Biophysics Reports, 2024, 10(2): 67-81. doi: 10.52601/bpr.2023.230024

Seeing is believing: observation of migrasomes

doi: 10.52601/bpr.2023.230024
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  • Corresponding author: liyulab@mail.tsinghua.edu.cn (L. Yu)
  • Received Date: 22 October 2023
  • Accepted Date: 29 December 2023
  • Available Online: 05 March 2024
  • Publish Date: 30 April 2024
  • Migrasomes are a novel type of cell organelle that form on the retraction fibers at the rear of migrating cells. In recent years, numerous studies have unveiled the mechanisms of migrasome formation and have highlighted significant roles of migrasomes in both physiological and pathological processes. Building upon the strategies outlined in published works and our own research experiences, we have compiled a comprehensive set of protocols for observing migrasomes. These step-by-step instructions encompass various aspects such as cell culture, labeling, imaging, in vitro reconstitution, and statistical analysis. We believe that these protocols serve as a valuable resource for researchers exploring migrasome biology.

  • Yuwei Huang and Li Yu declare that they have no conflict of interest.
    This article does not contain any studies with human or animal subjects performed by any of the authors.

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