Emerging two-dimensional material nanozymes for theranostic nanomedicine

Yanling You; Zhongmin Tang; Han Lin; Jianlin Shi

doi:10.52601/bpr.2021.210011

Volume 7 Issue 3

Jun. 2021

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Yanling You, Zhongmin Tang, Han Lin, Jianlin Shi. Emerging two-dimensional material nanozymes for theranostic nanomedicine[J]. Biophysics Reports, 2021, 7(3): 159-172. doi: 10.52601/bpr.2021.210011

Citation:

Yanling You, Zhongmin Tang, Han Lin, Jianlin Shi. Emerging two-dimensional material nanozymes for theranostic nanomedicine[J]. Biophysics Reports, 2021, 7(3): 159-172. doi: 10.52601/bpr.2021.210011

Yanling You, Zhongmin Tang, Han Lin, Jianlin Shi. Emerging two-dimensional material nanozymes for theranostic nanomedicine[J]. Biophysics Reports, 2021, 7(3): 159-172. doi: 10.52601/bpr.2021.210011

Citation:

Yanling You, Zhongmin Tang, Han Lin, Jianlin Shi. Emerging two-dimensional material nanozymes for theranostic nanomedicine[J]. Biophysics Reports, 2021, 7(3): 159-172. doi: 10.52601/bpr.2021.210011

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Emerging two-dimensional material nanozymes for theranostic nanomedicine

doi: 10.52601/bpr.2021.210011

Yanling You¹,
Zhongmin Tang^{2
,
,},
Han Lin^{1
,
,},
Jianlin Shi¹

1.
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China
2.
Center for Nanomedicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA

Funds: We greatly acknowledge the National Natural Science Foundation of China (52002391 and 21835007), Key Research Program of Frontier Sciences, Chinese Academy of Sciences (ZDBS-LY-SLH029), China Postdoctoral Science Foundation (2019M660098), and Science Foundation for Youth Scholar of State Key Laboratory of High Performance Ceramics and Superfine Microstructures (SKL201906).

More Information

Corresponding author: ztang3@bwh.harvard.edu (Z. Tang); linhan@mail.sic.ac.cn (H. Lin)
Received Date: 28 April 2021
Accepted Date: 20 May 2021

Available Online: 07 July 2021

Publish Date: 30 June 2021

Abstract

Abstract

Nanomaterials-based artificial enzymes (nanozymes) with valuable enzyme-like catalytic properties have been booming during the past few years. Promoted by the advances in biological medicine and nanotechnology, nanozymes possess the potential to serve as an emerging agent for biosensing, immunoassays, detection and diagnosis, catalytic therapeutics, and other applications in the biomedicine field. Two-dimensional (2D) nanomaterials are of considerable interest in biomedical applications due to their ultrathin layered structure and unique physiochemical properties. Inspired by the diversified catalytic performance of 2D nanomaterials, scientists extensively have developed 2D materials as bioactive nanozymes for theranostic nanomedicine. Here, recent advances in enzyme-like 2D nanomaterials design and construction are comprehensively presented. Additionally, we exhibit that, with the synergistic effect of catalytic activities and desirable physicochemical performances, 2D nanozymes can serve as versatile platforms with extensive applications from target detection to in vivo theranostic. It is believed that such promising alternatives towards natural enzymes will be of vital significance in the field of nanotechnology and biomedicine.
- Two-dimensional nanomaterials,
- Nanozymes,
- Nanomedicine

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References(74)

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