Exploring lysosomal biology: current approaches and methods

Qiuyuan Yin; Chonglin Yang

doi:10.52601/bpr.2023.230028

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Qiuyuan Yin, Chonglin Yang. Exploring lysosomal biology: current approaches and methods[J]. Biophysics Reports. doi: 10.52601/bpr.2023.230028

Citation:

Qiuyuan Yin, Chonglin Yang. Exploring lysosomal biology: current approaches and methods[J]. Biophysics Reports. doi: 10.52601/bpr.2023.230028

Qiuyuan Yin, Chonglin Yang. Exploring lysosomal biology: current approaches and methods[J]. Biophysics Reports. doi: 10.52601/bpr.2023.230028

Citation:

Qiuyuan Yin, Chonglin Yang. Exploring lysosomal biology: current approaches and methods[J]. Biophysics Reports. doi: 10.52601/bpr.2023.230028

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Exploring lysosomal biology: current approaches and methods

doi: 10.52601/bpr.2023.230028

Qiuyuan Yin^{1
,
,},
Chonglin Yang^{1, 2
,
,}

1.
State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan and Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, China
2.
Southwest United Graduate School, Kunming 650092, China

More Information

Corresponding author: qiuyuan_yin@ynu.edu.cn (Q. Yin); clyang@ynu.edu.cn (C. Yang)
Received Date: 28 October 2023
Accepted Date: 04 January 2024

Available Online: 26 February 2024

Abstract

Abstract

Lysosomes are the degradation centers and signaling hubs in the cell. Lysosomes undergo adaptation to maintain cell homeostasis in response to a wide variety of cues. Dysfunction of lysosomes leads to aging and severe diseases including lysosomal storage diseases (LSDs), neurodegenerative disorders, and cancer. To understand the complexity of lysosome biology, many research approaches and tools have been developed to investigate lysosomal functions and regulatory mechanisms in diverse experimental systems. This review summarizes the current approaches and tools adopted for studying lysosomes, and aims to provide a methodological overview of lysosomal research and related fields.
- Lysosome,
- Method,
- Cultured cell,
- C. elegans,
- Mice

Qiuyuan Yin and Chonglin Yang declare that they have no conflict of interest.
This article does not contain any studies with human or animal subjects performed by any of the authors.

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References(88)

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